GENEVA, Switzerland (AFP)— The risk posed by the Omicron variant is still “very high”, the World Health Organization said Wednesday, after COVID-19 case numbers shot up by 11 per cent globally last week.

Omicron is behind rapid virus spikes in several countries, including those where it has already overtaken the previously-dominant Delta variant, the WHO said in its COVID-19 weekly epidemiological update.

“The overall risk related to the new variant of concern Omicron remains very high,” the UN health agency said.

“Consistent evidence shows that the Omicron variant has a growth advantage over the Delta variant with a doubling time of two to three days and rapid increases in the incidence of cases is seen in a number of countries,” including Britain and the United States, where it has become the dominant variant.

“The rapid growth rate is likely to be a combination of both immune evasion and intrinsic increased transmissibility of the Omicron variant.”

However, the WHO highlighted the 29 per cent decrease in the incidence of cases observed in South Africa — the country which first reported the variant to the WHO on November 24.

It said early data from Britain, South Africa and Denmark — which currently has the world’s highest rate of infection per person — suggested there was a reduced risk of hospitalisation for Omicron compared to Delta.

However, further data was needed to understand Omicron’s severity in terms of clinical markers, including the use of oxygen, mechanical ventilation and death.

More data was also required on how the severity might be being impacted by previous COVID infection, or vaccination.

“It is also expected that corticosteroids and interleukin 6 receptor blockers will remain effective in the management of patients with severe disease,” the WHO said.

“However, preliminary data suggest that monoclonal antibodies may be less able to neutralise the Omicron variant.”

The WHO said that in the week ending Sunday, following a gradual increase since October, the global number of new cases rose by 11 per cent compared to the previous week, while the number of new deaths dipped by four per cent.

“This corresponds to just under five million new cases and over 44,000 new deaths,” the Geneva-based organisation said. 

The highest numbers of new cases were reported from the United States, Britain, France and Italy.