TUXTLA GUTIERREZ, Mexico (AP) — Rescue workers rushing to a highway accident found a horrific scene of death and injury after a freight truck jammed with as many as 200 migrants tipped over and crashed into the base of a steel pedestrian bridge in southern Mexico.

The migrants inside the cargo trailer were flipped, tossed and crushed into a pile that mingled the living and the dead.

By late Thursday, the death toll stood at 53, and authorities said at least 54 people had been injured. It was one of the worst single-day death tolls for migrants in Mexico since the 2010 massacre of 72 migrants by the Zetas drug cartel in the northern state of Tamaulipas.

Volunteer rescuers hauled bodies off the pile by their arms and legs, while some migrants scrambled and limped to extract themselves from the twisted steel sheets of the collapsed container.

One young man, pinned in a heap of unmoving bodies, wriggled to free the lower half of his frame from the weight of the dead piled atop him, his face wrenched into a grimace of life extracting itself from the clutches of death.

Nearby, a man blinked his eyes, unable to move as he lay on the shoulder of the road. Next to him was a fellow migrant, stouter and older, whose eyes no longer needed shading — they stared, startled and lifeless, unblinking, into the setting sun.

At the Vatican, Pope Francis, who visited Chiapas in 2015 and has made the plight of migrants a hallmark of his papacy, sent a telegram of condolences Friday to the archbishop of Tuxtla Gutierrez. In the note, he offered prayers for the victims, their families and the injured.

While the Mexican government is trying to appease the United States by stopping caravans of walking migrants and allowing the reinstatement of the “Remain in Mexico” policy, it hasn’t been able to stop the flood of migrants stuffed hundreds at a time into freight trucks operated by smugglers who charge thousands of dollars to take them to the U.S. border — trips that all too often lead them only to their deaths.

The most severely injured, many streaming blood, were carried by their arms and legs to plastic sheets set on the road. The walking wounded were led, stunned and uncomprehending, to the same sheets. Ambulances, cars and pickup trucks were dragooned into service, ferrying the injured to hospitals.

Later, the dead were laid in rows of white sheets, side by side, on the highway.

Rescue workers who first arrived said that even more migrants had been aboard the truck when it crashed and had fled for fear of being detained by immigration agents. One paramedic said some of those who hurried into surrounding neighbourhoods were bloodied or bruised, but still limped away in their desperation to escape.

About 200 migrants may have been packed into the truck, said Guatemala’s top human rights official, Jordán Rodas. While shocking, that number is not unusual for migrant smuggling operations in Mexico, and the sheer weight of the load — combined with speed and a nearby curve — may have been enough to throw the truck off balance, authorities said.

Luis Manuel Moreno, head of the Chiapas state civil defense office, said about 21 of the injured had serious wounds and were taken to local hospitals. The federal Attorney General’s Office said three were critically injured in the crash on a highway leading from the Guatemalan border toward the Chiapas state capital.

Sitting on the pavement beside the overturned trailer, survivor Celso Pacheco of Guatemala said the truck felt like it was speeding and then seemed to lose control under the weight of the migrants inside.

Pacheco said there were migrants mostly from Guatemala and Honduras aboard and estimated there were eight to 10 young children. He said he was trying to reach the United States, but now expected to be deported to Guatemala.

Marco Antonio Sánchez, director of the Chiapas Firefighter Institute, said ambulances raced victims to three hospitals, carrying three to four injured each. When there weren’t enough ambulances they loaded them into pickup trucks, he said.

Guatemalan President Alejandro Giammattei wrote on Twitter: “I deeply regret the tragedy in Chiapas state, and I express my solidarity for the victims’ families, to whom we will offer all the necessary consular assistance, including repatriation.”

The truck had originally been a closed freight module of the kind used to transport perishable goods. The container was smashed open by the force of the impact. It was unclear if the driver survived.

Those who spoke to survivors said the migrants told of boarding the truck in Mexico, near the border with Guatemala, and of paying between $2,500 and $3,500 to be transported to Mexico’s central state of Puebla. Once there, they would presumably have contracted with another set of migrant smugglers to take them to the U.S. border.

In recent months, Mexican authorities have tried to block migrants from walking in large groups toward the U.S. border, but the clandestine and illicit flow of migrant smuggling has continued.